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The Neurological Disorders Research Center (NDRC) is a new center within the Qatar Biomedical Research Institute (QBRI), and was launched in the summer of 2015. The NDRC focuses on investigating neurological disorders of increasing prevalence in Qatar and the region. These disorders are diverse and range from neurodevelopmental diseases such as Autism Spectrum Disorders (ASD); Intellectual Disability (ID); and epilepsy, to neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). The strategy of the center is to study these disorders based on the following themes:
The NDRC is a pioneer neuroscience center in Qatar and the region that aims to study neurological disorders of significance importance. Furthermore, the NDRC has the potential to greatly impact the visibility of neurological disorders in Qatar and the surrounding region, not only by bringing new treatments and hope to patients, but by also significantly accelerating the pace of therapeutic development using technologies, such as experimental disease modeling, biomarker analyses, gene therapy, and stem cell biology.
The key vision of the NDRC is to develop an international center of excellence from basic to applied research in CNS diseases and establish strong partnerships with existing academic research groups, government research-funding agencies, and the healthcare sector. The NDRC will achieve the following objectives:
These objectives are based on the tremendous need for improving healthcare within Qatar. This will be accomplished by sharing expertise as well as the know-how of diverse techniques such as genomics, epigenomics, proteomics, stem cell biology, and electrophysiology towards answering unresolved scientific questions and developing clinical outcomes related to these disorders. Altogether, this enables fundamental research with results fast-forwarded into translational and/or therapeutic applications, which will have a better outcome for the Qatari population.
Prof. Omar El-Agnaf
Scientific Director of QBRI-NDRC
Full professor at HBKU
Identification of novel biomarkers for diagnosis and prognosis of neurodevelopmental disorders and neurodegenerative diseases
Prof. Omar Albagha
Identify the genetic components of neurological disorders in Qatar
Dr. Fouad Al Shaban
Study the incidence and prevalence of neurological disorders in Qatar
Dr. Tariq Ahmed
Investigating Synaptic physiology of neurological disorders
Dr. Mohamed Emara
Modeling neurodevelopmental disorders and neurodegenerative diseases using induced pluripotent stem cells (iPSCs) technology
Dr. Sara Abdulla
Dr. Abeer Al-Shammari
QBRI is currently looking to recruit highly-skilled individuals for a number of roles.
Inger van Steenoven, Nour K. Majbour, Nishant Vaikath, Henk W. Berendse, Wiesje M. van der Flier, Wilma D.J. van de Berg, Charlotte E. Teunissen, Afina W. Lemstra, and Omar M.A. El-Agnaf
Journal: Movement Disorders. Article DOI: 10.1002/mds.111, Article ID: MDS111, Internal Article ID: 15859369
Caroline Spasojevic, Elisabetta Marangoni, Sophie Vacher, Franck Assayag, Didier Meseure, Sophie Château-Joubert, Martine Humbert, Manale Karam, Jean Marc Ricort, Christian Auclair, Marie Regairaz and Ivan Bièche (2018).
Oncotarget. Doi: 10.18632/oncotarget.25292
Ali Abouelghar, Reem Hasnah, Ghina Taouk, Mohamad Saad and Manale Karam (2018).
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